Small Molecules Take A Big Step Against Clostridium difficile

• Autores: Greg L. Beilhartz, John Tam -, Roman A. MeInyk
• Localización: Trends in microbiology, ISSN 0966-842X, Vol. 23, Nº. 12, 2015, págs. 746-748
• Idioma: inglés
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• Resumen

  • Effective treatment of Clostridium difficile infections demands a shift away from antibiotics towards toxin-neutralizing agents. Work by Bender et al., using a drug that attenuates toxin action in vivo without affecting bacterial survival, demonstrates the exciting potential of small molecules as a new modality in the fight against C. difficile.Effective treatment of Clostridium difficile infections demands a shift away from antibiotics towards toxin-neutralizing agents. Work by Bender et al., using a drug that attenuates toxin action in vivo without affecting bacterial survival, demonstrates the exciting potential of small molecules as a new modality in the fight against C. difficile.