Do not scratch that mole!

• Autores: Mark Jelcic, Philipp Niethammer
• Localización: Trends in immunology, ISSN 1471-4906, Vol. 36, Nº. 9, 2015, págs. 503-504
• Idioma: inglés
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• Resumen

  • Nevi harbor some of the same oncogene mutations that also drive malign melanoma. Further tumor promoting events are required to unleash their carcinogenic potential. Using zebrafish whose melanocytes overexpress an HRAS-oncogene, a new study reports that injury induces melanoma, possibly through recruitment of neutrophils that trigger proliferation of preneoplastic melanocytes.