The Regulatory T Cell: Jack-Of-All-Trades

• Autores: Ajithkumar Vasanthakumar, Axel Kallies
• Localización: Trends in immunology, ISSN 1471-4906, Vol. 36, Nº. 12, 2015, págs. 756-758
• Idioma: inglés
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• Resumen

  • Foxp3+ regulatory T (Treg) cells suppress auto-reactive and inflammatory T cells to maintain immune homeostasis. In a recent study, Rudensky and colleagues demonstrate the ability of Treg cells to facilitate tissue repair, a non-canonical Treg cell function accomplished by amphiregulin and mediated by cytokines interleukin (IL)-18 and IL-33.