The Use of Interferons in the Treatment of Cutaneous T-Cell Lymphoma

• Autores: Natalie Spaccarelli, Alain H. Rook
• Localización: Dermatologic clinics, ISSN 0733-8635, Vol. 33, Nº. 4, 2015 (Ejemplar dedicado a: Cutaneous Lymphoma), págs. 731-745
• Idioma: inglés
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• Resumen

  • Interferons are polypeptides that naturally occur in the human body as a part of the innate immune response. By harnessing these immunomodulatory functions, synthetic interferons have shown efficacy in combating various diseases including cutaneous T-cell lymphoma. This article closely examines the qualities of interferon alfa and interferon gamma and the evidence behind their use in the 2 most common types of cutaneous T-cell lymphomas, namely, mycosis fungoides and Sézary syndrome.