The Discovery-Oriented Approach to Organic Chemistry. 5. Stereochemistry of E2 Elimination: Elimination of cis- and trans-2-Methylcyclohexyl Tosylate

Marcus E. Cabay ^[1] ; Brad J. Ettlie ^[1] ; Adam J. Tuite ^[1] ; Kurt A. Welday ^[1] ; Ram S. Mohan ^[1]
1. [1] Illinois Wesleyan University
  
  Illinois Wesleyan University
  
  Township of Bloomington City, Estados Unidos
Localización: Journal of chemical education, ISSN 0021-9584, Vol. 78, Nº 1, 2001, pág. 79
Idioma: inglés
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Resumen
- The E2 elimination is one of the most important reactions in organic chemistry and is discussed in considerable detail in a sophomore organic course. We have developed a discovery-oriented lab that illustrates the stereochemistry of the E2 elimination reaction and is a good exercise in 1H NMR spectroscopy. The added element of discovery insures that student interest and enthusiasm are retained.