Statins and Cognitive Side Effects: What Cardiologists Need to Know

• Autores: Carlos Rojas Fernandez, Zain Hudani, Vera A. Bittner
• Localización: Endocrinology and metabolism clinics of North America, ISSN 0889-8529, Vol. 45, Nº. 1, 2016 (Ejemplar dedicado a: Lipidology), págs. 101-116
• Idioma: inglés
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• Resumen

  • Statins are widely used in secondary and primary prevention of atherosclerotic cardiovascular disease. They reduce cardiovascular events and mortality, and have an excellent safety record. Recent case reports suggest a possible association between statins and adverse effects on cognition. This article reviews recent literature related to statins and cognition and provides recommendations to clinicians. Cognitive considerations should not play a role in decision making for most patients for whom statins are indicated. Future trials of statin, or any novel antilipemic agent should include systematic assessment of cognition.