Hemodynamics of Cerebral Aneurysms

• Daniel M. Sforza ^[3] ; Christopher M. Putman ^[1] ; Juan Raul Cebral ^[2]
  1. [1] Inova Fairfax Hospital

     Inova Fairfax Hospital

     Estados Unidos

     
  2. [2] George Washington University

     George Washington University

     Estados Unidos

     
  3. [3] George Mason University

     George Mason University

     Estados Unidos

     

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• Localización: Annual review of fluid mechanics, ISSN 0066-4189, Nº. 41, 2009, págs. 91-107
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • The initiation and progression of cerebral aneurysms are degenerative processes of the arterial wall driven by a complex interaction of biological and hemodynamic factors. Endothelial cells on the artery wall respond physiologically to blood-flow patterns. In normal conditions, these responses are associated with nonpathological tissue remodeling and adaptation. The combination of abnormal blood patterns and genetics predisposition could lead to the pathological formation of aneurysms. Here, we review recent progress on the basic mechanisms of aneurysm formation and evolution, with a focus on the role of hemodynamic patterns.