Current Diagnostic Trends in Coagulation Disorders Among Dogs and Cats

• Autores: Marjory B. Brooks, James L. Catalfamo
• Localización: Veterinary Clinics of North America: Small Animal Practice: Small Animal Practice, ISSN-e 0195-5616, Vol. 43, Nº. 6, 2013 (Ejemplar dedicado a: Clinical Pathology and Diagnostic Testing), págs. 1349-1372
• Idioma: inglés
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• Resumen

  • The diagnostic workup to differentiate hemorrhage caused by vascular injury from a systemic hemostatic imbalance typically involves a combination of broad screening tests and specific assays. The characterization of 3 overlapping phases of primary hemostasis, secondary hemostasis, and fibrinolysis provides a simple diagnostic framework for evaluating patients with clinical signs of hemorrhage. New techniques such as flow cytometry, thrombin-generation assays, thrombelastography, and anticoagulant drug monitoring are under investigation for veterinary patients; however, their ability to improve diagnosis or treatment requires further study in clinical trials.