The Epidemiology of Clostridium difficile Infection Inside and Outside Health Care Institutions

• Autores: Dale N. Gerding, Fernanda C. Lessa Lessa
• Localización: Infectious disease clinics of North America, ISSN 0891-5520, Vol. 29, Nº. 1, 2015 (Ejemplar dedicado a: Clostridium difficile Infection), págs. 37-50
• Idioma: inglés
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• Resumen

  • This article describes the global changes in Clostridium difficile epidemiology since the late twentieth century and into the twenty-first century when the new epidemic strain BI/NAP1/027 emerged. The article provides an overview of how understanding of C difficile epidemiology has rapidly evolved since its initial association with colitis in 1974. It also discusses how C difficile has spread across the globe, the role of asymptomatic carriers in disease transmission, the increased recognition of C difficile outside health care settings, the changes in epidemiology of C difficile infection in children, and the risk factors for disease.