Quantifying Current Events Identifies a Novel Endurance Regulator

• Autores: Theresa C. Henry, Mark P. Brynildsen
• Localización: Trends in microbiology, ISSN 0966-842X, Vol. 24, Nº. 5, 2016, págs. 324-326
• Idioma: inglés
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• Resumen

  • In nongrowing microbes, proteome turnover is reduced and identification of newly synthesized, low-abundance proteins is challenging. Babin and colleagues recently utilized bio-orthogonal noncanonical amino acid tagging (BONCAT) to identify actively synthesized proteins in nongrowing Pseudomonas aeruginosa, discovering a regulator whose influences range from biofilm formation to secondary metabolism.