Indications and procedures for direct immunofluorescence biopsies of the oral mucosa

• Autores: José Luis Tapia, Lakshmanan Suresh, Mirdza E. Neiders
• Localización: Quintessence International, ISSN-e 0033-6572, Vol. 46, Nº. 3, 2015, págs. 247-253
• Idioma: inglés
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• Resumen

  • A definitive diagnosis is crucial for management of any oral mucosal disease. Direct immunofluorescence (DIF) is a valuable diagnostic aid for immune-mediated blistering diseases and systemic connective tissue diseases of the skin and the mucosa. This paper gives an overview of the DIF biopsy technique for oral lesions and provides a background for the clinician to optimize the utilization of DIF biopsy. The key characteristic diagnostic findings of DIF of specific mucosal diseases are also discussed.