Resumen de Mass Spectral Fragmentation Patterns of Deuterated Butyl and Ethyl Acetates: An Easy Microscale Isotopic Labeling Experiment

Hengameh Zahedkargaran, Leverett R. Smith

• We have developed an experimentally uncomplicated microscale second-semester organic lab exercise that illustrates the use of isotopic labeling, in this case deuteration, to help confirm and interpret mass spectral fragmentation patterns in butyl acetate and ethyl acetate. Preparation and gas chromatographic-mass spectrometric (GC-MS) analysis of unlabeled and labeled esters is followed by pooling of student data for interpretation and write-up.