Effect of the Use of Ambulance-Based Thrombolysis on Time to Thrombolysis in Acute Ischemic Stroke A Randomized Clinical Trial

• Autores: Martin Ebinger, Benjamin Winter, Matthias Wendt, Joachim E. Weber, Carolin Waldschmidt
• Localización: JAMA: the journal of the American Medical Association, ISSN 0098-7484, Vol. 311, Nº. 16, 2014, págs. 1622-1631
• Idioma: inglés
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• Resumen

  • Importance Time to thrombolysis is crucial for outcome in acute ischemic stroke.

    Objective To determine if starting thrombolysis in a specialized ambulance reduces delays.

    Design, Setting, and Participants In the Prehospital Acute Neurological Treatment and Optimization of Medical care in Stroke Study (PHANTOM-S), conducted in Berlin, Germany, we randomly assigned weeks with and without availability of the Stroke Emergency Mobile (STEMO) from May 1, 2011, to January 31, 2013. Berlin has an established stroke care infrastructure with 14 stroke units. We included 6182 adult patients (STEMO weeks: 44.3% male, mean [SD] age, 73.9 [15.0] y; control weeks: 45.2% male, mean [SD] age, 74.3 [14.9] y) for whom a stroke dispatch was activated.