Sofosbuvir and Ribavirin for Hepatitis C in Patients With HIV Coinfection

• Autores: Mark Sulkowski, Susanna Naggie, Jacob P. Lalezari, Walford Jeffrey Fessel, Karam Mounzer
• Localización: JAMA: the journal of the American Medical Association, ISSN 0098-7484, Vol. 312, Nº. 4, 2014, págs. 353-361
• Idioma: inglés
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• Resumen

  • Importance Treatment of hepatitis C virus (HCV) infection in patients also infected with human immunodeficiency virus (HIV) has been limited due to drug interactions with antiretroviral therapies (ARTs) and the need to use interferon.

    Objective To determine the rates of HCV eradication (sustained virologic response [SVR]) and adverse events in patients with HCV-HIV coinfection receiving sofosbuvir and ribavirin treatment