This review refers to the Silphium (Apiaceae), one of the most enigmatic plants in the history of the Mediterranean. In Greco-Roman world, it was a panacea and especially, a powerful aphrodisiac which left many written historical references, in addition to their image mosaics and coins. Silphium extinction, due to over-exploitation is certainly a good example for the conservation of biodiversity and for the defense of sustainable use of natural resources.
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