Regulation of Bacterial Peptidoglycan Polymerization

• Autores: Michel Arthur
• Localización: Trends in microbiology, ISSN 0966-842X, Vol. 24, Nº. 7, 2016, págs. 519-521
• Idioma: inglés
• Enlaces
  • Texto completo
• Resumen

  • How bacterial cells control the activity of peptidoglycan polymerases has remained mysterious. Biochemical characterization of derivatives of penicillin-binding protein PBP1b that are functional in the absence of lipoprotein LpoB provides evidence for allosteric control of PBP1b glycosyltransferase activity via binding of LpoB to the PBP1b UBH1 domain.