Game of Trans-Kingdom Effectors

• Autores: Sophie Bleves
• Localización: Trends in microbiology, ISSN 0966-842X, Vol. 24, Nº. 10, 2016, págs. 773-774
• Idioma: inglés
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• Resumen

  • TplE, a type VI secreted (phospho)lipase, has been identified as the third trans-kingdom effector of Pseudomonas aeruginosa, targeting both prokaryotic and eukaryotic hosts. Indeed, TplE triggers the killing of bacterial competitors and promotes autophagy in epithelial cells once localized to the endoplasmic reticulum.