Resumen de Critical role for hyperpolarization-activated cyclic nucleotide-gated channel 2 in the AIF-mediated apoptosis
Erik Norberg, Marie Karlsson, Olga Korenovska, Susanne Szydlowski, Gilad Silberberg, Per Uhlén, Sten Orrenius, Boris Zhivotovsky
This study establishes HCN2 channels as physiological relevant ‘calcium gates' that mediate apoptosis-inducing factor-dependent cell death in cancer and primary neuronal cells.
