Replication termination and chromosome dimer resolution in the archaeon Sulfolobus solfataricus

• Iain G Duggin ^[2] ; Nelly Dubarry ^[1] ; Stephen D Bell ^[1]
  1. [1] Sir William Dunn School of Pathology, Oxford University, Oxford, UK
  2. [2] Sir William Dunn School of Pathology, Oxford University, Oxford, UK; MRC Cancer Cell Unit, Hutchison/MRC Research Centre, Cambridge, UK
• Localización: EMBO journal: European Molecular Biology Organization, ISSN 0261-4189, Vol. 30, Nº. 1, 2010, págs. 145-153
• Idioma: inglés
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• Resumen

  • Eubacteria and archaea possess single-circular chromosomes, yet some archaea resemble eukaryotes in using multiple origins and replication forks. Replication termination in Sulfolobus is found to occur by stochastic collision of these forks, and—unlike the situation in eubacteria—it is not linked to chromosome segregation.