Large ring polymers align FtsZ polymers for normal septum formation

• Muhammet E Gündoğdu ^[3] ; Yoshikazu Kawai ^[4] ; Nada Pavlendova ^[5] ; Naotake Ogasawara ^[1] ; Jeff Errington ^[3] ; Dirk-Jan Scheffers ^[2] ; Leendert W Hamoen ^[3]
  1. [1] Nara Institute of Science and Technology

     Nara Institute of Science and Technology

     Japón

     
  2. [2] Universidade Nova de Lisboa

     Universidade Nova de Lisboa

     Socorro, Portugal

     
  3. [3] Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle, UK
  4. [4] Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle, UK; Nara Institute of Science and Technology, Graduate School of Information Science Functional Genomics, Ikoma, Japan
  5. [5] Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle, UK; Institute of Molecular Biology, Slovak Academy of Sciences, Bratislava, Slovak Republic

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• Localización: EMBO journal: European Molecular Biology Organization, ISSN 0261-4189, Vol. 30, Nº. 3, 2011, págs. 617-626
• Idioma: inglés
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• Resumen

  • The bacterial cell division protein FtsZ assembles into a circular structure at the site of cell division. SepF is important for cell division, but how it functions is not clear. Here, the findings show that SepF polymerizes into large rings that promote the assembly of FtsZ during septum formation.