Resumen de Molecular mechanism of Ena/VASP-mediated actin-filament elongation

Dennis Breitsprecher, Antje K. Kiesewetter, Joern Linkner, Marlene Vinzenz, Theresia E.B. Stradal, J. Victor Small, Ute Curth, Richard B. Dickinson, Jan Faix

• Ena/VASP proteins have important functions in actin-dependent processes. A model for the actin elongation activity of Ena/VASP based on the affinity and saturation state of WH2-domain-mediated actin monomer binding is presented.