Resumen de Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells
Diana M Vallejo, Esther Caparrós Cayuela
, Maria Dominguez
A genetic screen in Drosophila uncovers miR-8 as an inhibitor of Notch-induced overgrowth, and identifies a conserved regulatory network comprising the Notch pathway, ZEB1 and this miRNA regulating metastasis and proliferation in flies and cancer cells. See also Brabletz et al in this issue.
