Resumen de Small RNA-mediated regulation of iPS cell generation

Zhonghan Li, Chao Yang, Katsuhiko Nakashima, Tariq M. Rana

• The generation of induced pluripotent stem cells is limited by the low reprogramming efficiency of somatic cells. Here, three clusters of miRNAs are shown to enhance reprogramming efficiency by targeting the TGF-β and p53 pathways, which inhibit the process.