Resumen de PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution

Yuwen Ke, Jae-Wan Huh, Ross Warrington, Bing Li, Nan Wu, Mei Leng, Junmei Zhang, Haydn Ball, Hongtao Yu

• The helicase proteins PICH and BLM localize to ultrafine DNA threads between separating sister chromatids. It now appears they cooperate to remove histones from these anaphase DNA bridges, to allow their stretching and unravelling without breakage.