Resumen de Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity

Mandy Miertzschke, Carolin Koerner, Ingrid R. Vetter, Daniela Keilberg, Edina Hot, Simone Leonardy, Lotte Søgaard Andersen, Alfred Wittinghofer

• The small G protein MglA and its cognate GAP MglB exemplify a new type of GTPase activation mechanism. In contrast to other Ras-like proteins, the key 'arginine finger' is provided not by the GAP, but by MglA itself.