Resumen de ARF6-mediated endosomal transport of Telencephalin affects dendritic filopodia-to-spine maturation

Tim Raemaekers, Aleksandar Peric, Pieter Baatsen, Ragna Sannerud, Ilse Declerck, Veerle Baert, Christine Michiels, Wim Annaert

• The GTPase Arf6 and its exchange factor EFA6A promote internalization of the Ig-like molecule Telencephalin in hippocampal neurons leading to the maturation of filopodia into dendritic spines, important for synapse formation.