As nonrenewable resources deplete and educators seek relevant interdisciplinary content for organic chemistry instruction, biobased laboratory experiments present themselves as potential alternatives to petroleum-based transformations, which offer themselves as sustainable variations on important themes. Following the principles of green chemistry and the powerful biorefinery model it is possible to create pedagogically sound and modern laboratory experiments employing readily available renewable reactants and reagents to convey important organic chemistry principles. In a reverse approach compared to total synthesis, these experiments should serve to not only make the undergraduate organic chemistry laboratory more green and sustainable but also educate the next generation with both historically important developments and cutting-edge research.
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