Correlation between canine inflammatory bowel disease activity indices after stem cell therapy

• Autores: Eva María Pérez Merino
• Localización: Veterinary Record, ISSN-e 2042-7670, Vol. 179, Nº. 18, 2016, págs. 464-464
• Idioma: inglés
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• Resumen

  • DISPARITY between the magnitude of the clinical response, the endoscopic mucosal appearance and the histological reduction of gastrointestinal inflammation after conventional therapy in dogs with inflammatory bowel disease (IBD) is a phenomenon commonly described (Willard and Mansell 2011). Although adipose-derived stem cells (ASCs) have recently been demonstrated to improve clinical, endoscopic and histological signs of canine IBD (Perez-Merino and others 2015a, b), the agreement between the clinical response and the degree of mucosal healing after this new therapy has never been investigated and would indicate its true degree of effectiveness. Thus, the authors’ aim was to assess the correlation between clinical, endoscopic and histological activity in dogs with IBD treated with stem cells.