Coagulopathy and bleeding in liver disease

• Autores: Vipul Jairath
• Localización: Medicine, ISSN-e 1357-3039, Vol. 43, Nº. 11, 2016, págs. 664-665
• Idioma: inglés
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• Resumen

  • One of the many complications of cirrhosis is the development of a complex disorder of haemostasis with abnormal coagulation indices such as prolonged prothrombin time and low platelet count. Greater understanding of the thrombotic complications of cirrhosis has altered our traditional perception of liver disease as a pro-haemorrhagic disorder. Coagulation status in cirrhosis is now thought to be re-balanced in the stable state, but easily tipped towards a bleeding or thrombotic event in the setting of an appropriate trigger, such as hospitalization or infection.