The Application of Voltammetric Analysis of D 9 -THC for the Reduction of False Positive Results in the Analysis of Suspected Marijuana Plant Matter
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Marco A. Balbino [1] ; Laura S. de Oliveira [1] ; Izabel C. Eleotério [1] ; Erica N. Oiye [1] ; Maria F.M. Ribeiro [1] ; Bruce R. McCord [2] ; Antonio J. Ipolito [3] ; Marcelo F. de Oliveira [1]
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[1] Universidade de São Paulo
Universidade de São Paulo
Brasil
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[2] Florida International University
Florida International University
Estados Unidos
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[3] Núcleo de Perícias Criminalísticas de Ribeirão Preto Superintendência de Polícia Técnico‐Científica do Estado de São Paulo Ribeirão Preto SP Brasil
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- Localización: Journal of forensic sciences, ISSN-e 1556-4029, ISSN 0022-1198, Vol. 61, Nº. 4, 2016, págs. 1067-1073
- Idioma: inglés
- Texto completo no disponible (Saber más ...)
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Resumen
The development of methodologies using inexpensive, fast, and reliable instrumention is desirable in illicit drug analysis. The purpose of this study was based on cyclic voltammetry technique to differentiate the electrochemical behavior of ∆9-THC, the psychoactive substance in marijuana, and five different extract plants to yield false positive results after analysis protocol for cannabinoids using thin-layer chromatography and Fast Blue B salt. After applying a deposition potential of 0.5 V in a glassy carbon working electrode, the results indicated an anodic peak current at 0.0 V versus Ag/AgCl after addition of ∆9-THC solution in the electrochemical cell, and limits of detection and quantification were 1.0 ng mL -1 and 3.5 ng mL-1, respectively. Other interfering plants showed distinct amperometric responses. This methodology was useful to detect ∆9-THC even in the presence of the Fast Blue B salt, which avoided false positive results for all the studied extract plants.
