Using Esters To Introduce Paradigms of Spin–Spin Coupling

• Kyle T. Smith ^[1] ; Christian S. Hamann ^[1]
  1. [1] Albright College

     Albright College

     City of Reading, Estados Unidos

     
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 94, Nº 1, 2017, págs. 126-130
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Students analyzed a set of 34 carboxylic esters using 1H nuclear magnetic resonance (NMR) spectroscopy to examine paradigmatic examples of spin–spin coupling, a foundational concept used to determine molecular structure by NMR spectroscopy. The ester functional group provides excellent chemical shift dispersion so that students were able to analyze well-resolved peaks and to apply concepts of chemical shift, line shape, and integration to the analysis of molecular substructures. A laboratory activity combining molecular models, worksheets, and NMR data collection and analysis provided students with the ability to predict and to analyze spectra representing spin–spin splitting for N = 0–6 (where N is the number of three-bond neighbors that are hydrogens).