Resumen de Interferon-I: The Pièce de Résistance of HIV-1 Transmission?
Damien C. Tully, Daniel T. Claiborne, Todd M. Allen
Despite the extensive viral quasispecies that develops in an individual during the course of HIV-1 infection, transmission is typically established by a single donor viral variant. Recent studies now provide insight into the phenotypic properties influencing this selection process at transmission, including the contribution of resistance to type I interferons.
