Clinicopathological analysis of oral mucous autoimmune disease: a 27-year study
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Emília Angela Loschiavo Arisawa [1] ; Janete Dias Almeida [2] ; Yasmin Rodarte Carvalho [2] ; Luiz Antonio Guimarães Cabral [2]
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[1] Vale do Paraíba University - UNIVAP
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[2] São Paulo State University - UNESP
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- Localización: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, ISSN-e 1698-6946, Vol. 13, Nº. 2, 2008
- Idioma: inglés
- Enlaces
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Resumen
Objectives: The aim of the present study was to analyze the main clinical and histopathological features of autoimmune diseases with oral manifestations such as oral lichen planus (OLP); mucous membrane pemphigoid (MMP);
pemphigus vulgaris (PV) and erythema multiforme (EM).
Study design: Retrospective review of 5770 files from the Oral Pathology Laboratory of São José dos Campos Dental School, São Paulo State University (UNESP) comprising a 27-year period from 1974 to 2000.
Results: The cases accounted for 64 (1.10%) of 5770 anatomopathological examinations performed over the study period. Among the autoimmune diseases diagnosed, 49 (76.56%) were OLP, 6 (9.37%) were MMP, 5 (7.82%) were EM and 4 (6.25%) were PV. Descriptive statistical analysis was used.
Conclusion: The initial manifestations of most autoimmune diseases occur in the oral mucosa. An earlier diagnosis and proper therapeutic protocol will delay the dissemination of the lesions, thus greatly contributing to a better prognosis and quality of life of the patient.
