Acknowledging and Overcoming Nonreproducibility in Basic and Preclinical Research

• Autores: John P. A. Ioannidis
• Localización: JAMA: the journal of the American Medical Association, ISSN 0098-7484, Vol. 317, Nº. 10, 2017, págs. 1019-1020
• Idioma: inglés
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• Resumen

  • The evidence for nonreproducibility in basic and preclinical biomedical research is compelling. Accumulating data from diverse subdisciplines and types of experimentation suggest numerous problems that can create a fertile ground for nonreproducibility.1 For example, most raw data and protocols are often not available for in-depth scrutiny and use by other scientists. The current incentive system rewards selective reporting of success stories.