Hepatitis C and autoimmunity: a therapeutic challenge

• Autores: B.C. Böckle, M. Baltaci, G. Ratzinger, I. Graziadei, W. Vogel, N.T. Sepp
• Localización: Journal of Internal Medicine, ISSN-e 1365-2796, Vol. 271, Nº. 1, 2012, págs. 104-106
• Idioma: inglés
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• Resumen

  • Abstract.  Böckle BC, Baltaci M, Ratzinger G, Graziadei I, Vogel W, Sepp NT (Innsbruck Medical University, Anichstrasse, Innsbruck, Austria). Hepatitis C and autoimmunity: a therapeutic challenge (Case Report). J Intern Med 2012; 271: 104–106.

    Hepatitis C virus (HCV) infection causes not only acute and chronic liver disease, but also extrahepatic symptoms. To our knowledge, this is the first case report of a patient who developed simultaneously subacute cutaneous lupus erythematosus and a small CD20+ B-cell clone because of chronic HCV infection and relapse after standard of care therapy (pegylated interferon plus ribavirin). Treatment with rituximab, a chimeric anti-CD20 monoclonal antibody, was successful.