Antipsychotics

• Autores: Kalliopi Vallianatou
• Localización: Medicine, ISSN-e 1357-3039, Vol. 44, Nº. 12, 2016, págs. 748-752
• Idioma: inglés
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• Resumen

  • Antipsychotics are the mainstay of psychosis treatment. They are also used in the acute and long-term treatment of bipolar disorder, in depression and other conditions. They are classified as first-generation (‘typical’) and second-generation (‘atypical’) antipsychotics based on their ability to cause extrapyramidal symptoms (EPS). Metabolic adverse effects occur mainly with second-generation antipsychotics. Both classes have broadly similar efficacy in controlling the symptoms of psychosis with the exception of clozapine, which is unique in its improved efficacy in treatment-resistant schizophrenia.