Biochemical Testing Relevant to Bone

• Autores: Chee Kian Chew, Bart L. Clarke
• Localización: Endocrinology and metabolism clinics of North America, ISSN 0889-8529, Vol. 46, Nº. 3, 2017 (Ejemplar dedicado a: Biochemical and Imaging Diagnostics in Endocrinology), págs. 649-667
• Idioma: inglés
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• Resumen

  • Laboratory biochemical testing is critical to the clinical understanding of bone disorders. Patients with skeletal diseases have underlying themes in their pathophysiology that would be impossible to detect without biochemical assessment of serum and urine minerals, vitamin D, parathyroid hormone, parathyroid hormone–related peptide, and bone turnover markers. Bone disorders are caused by abnormalities in signaling pathways that affect bone formation and resorption. Therapies for common bone diseases were developed in direct response to underlying biochemical abnormalities.