Recent developments in radiotherapy for small-cell lung cancer: a review by the Oncologic Group for the Study of Lung Cancer (Spanish Radiation Oncology Society)
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N. Rodriguez de Dios [1] ; P. Calvo [5] ; M. Rico [2] ; M. Martín [3] ; F. Couñago [6] ; A. Sotoca [4] ; B. Taboada [5] ; A. Rodríguez [4]
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[1] Hospital del Mar
Hospital del Mar
Barcelona, España
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[2] Gobierno de Navarra
Gobierno de Navarra
Pamplona, España
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[3] Hospital Ramón y Cajal
Hospital Ramón y Cajal
Madrid, España
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[4] Hospital Ruber Internacional
Hospital Ruber Internacional
Madrid, España
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[5] Hospital Universitario Santiago de Compostela, España
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[6] Hospital Universitario Quirón Madrid, España
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- Localización: Clinical & translational oncology, ISSN 1699-048X, Vol. 19, Nº. 10 (October 2017), 2017, págs. 1183-1192
- Idioma: inglés
- Texto completo no disponible (Saber más ...)
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Resumen
Small-cell lung cancer (SCLC) accounts for 13% of all lung tumours. The standard treatment in patients with limited-stage disease is radiotherapy combined with chemotherapy. In extensive SCLC, the importance of consolidation thoracic radiotherapy in patients with a good treatment response has become increasingly recognized. In both limited and extensive disease, prophylactic cranial irradiation is recommended in patients who respond to treatment. New therapeutic approaches such as immunotherapy are being increasingly incorporated into the treatment of SCLC, although more slowly than in non-small cell lung cancer (NSCLC). Diverse radiation dose and fractionation schemes, administered in varying combinations with these new drugs, are being investigated. In the present study we review and update the role of radiotherapy in the treatment of SCLC. We also discuss the main clinical trials currently underway in order to identify future trends.
