Resumen de Enterocolitis neutropénica en niños

Jaime Fernández Sarmiento, Carolina Casas, Javier Godoy

• español

  Neutropenic Enterocolitis (NE) is a heterogeneous disease with wide range of clinical presentation that can affect any segment of the gastrointestinal tract, with varying severity. It is a complication in patients with high-dose chemotherapy for hematologic and solid tumors. NE typically presents with fever and abdominal pain, but diagnosing is still challenging because symptoms can be varied and elusive. A high index of suspicion must be maintained. The early study with computed tomography directs diagnosis. Most patients benefit from conservative treatment consisting on bowel rest, nasogastric tube placement, parenteral nutritional support, analgesic and broad-spectrum antibiotic coverage. However, the surgical intervention is uncommon and is limited to perforation, peritonitis or gastrointestinal bleeding despite correction of coagulopathy.

• English

  Neutropenic Enterocolitis (NE) is a heterogeneous disease with wide range of clinical presentation that can affect any segment of the gastrointestinal tract, with varying severity. It is a complication in patients with high-dose chemotherapy for hematologic and solid tumors. NE typically presents with fever and abdominal pain, but diagnosing is still challenging because symptoms can be varied and elusive. A high index of suspicion must be maintained. The early study with computed tomography directs diagnosis. Most patients benefit from conservative treatment consisting on bowel rest, nasogastric tube placement, parenteral nutritional support, analgesic and broad-spectrum antibiotic coverage. However, the surgical intervention is uncommon and is limited to perforation, peritonitis or gastrointestinal bleeding despite correction of coagulopathy.