Feline Cardiogenic Arterial Thromboembolism: Prevention and Therapy

• Autores: Daniel F. Hogan
• Localización: Veterinary Clinics of North America: Small Animal Practice: Small Animal Practice, ISSN-e 0195-5616, Vol. 47, Nº. 5, 2017, págs. 1065-1082
• Idioma: inglés
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• Resumen

  • Feline cardiogenic arterial thromboembolism (CATE) is a clinically devastating disease.

    Cats with underlying cardiac disease appear to be predisposed to formation of intracavitary thrombi due to blood stasis, endothelial injury and a hypercoagulable state.

    The two major categories of antithrombotic drugs are antiplatelet agents and anticoagulants.

    Clopidogrel was shown to be superior to aspirin, with a lower CATE recurrence rate and longer median time to CATE.

    The management of acute CATE includes: induction of a hypocoagulable state to reduce continued thrombus formation; improve blood flow to the infarcted arterial bed; provide pain management; treat concurrent congestive heart failure if present, and provide supportive care.

    The clinical signs of CATE are dramatic and acute survival is relatively low, but most cats are fairly stable within 48-72 hours. Therefore, owners should consider therapy for at least the first 72 hours and not make a decision for immediate euthanasia.