Update on Crystal-Induced Arthritides

• Autores: Hossam El Zawawy, Brian F. Mandell
• Localización: Clinics in geriatric medicine, ISSN 0749-0690, Vol. 33, Nº. 1, 2017, págs. 135-144
• Idioma: inglés
• Enlaces
  • Texto Completo Ejemplar
• Resumen

  • The prevalence of gout increases with age. Once serum concentration of urate exceeds the saturation/solubility point, it deposits in and around the joints. Clinical presentation in the elderly often has “atypical” features and is challenging to diagnose. Treatment depends on the stage of the disease and the patient’s health status and comorbidities. Elderly patients often have several confounding issues; thus, treatment decisions can be complicated and therapeutic options limited. To prevent the recurrence of gout attacks, serum concentration of urate should be maintained well below the saturation threshold of 6.8 mg/dL, leading to dissolution of urate deposits and prevent recurrence.