TRAPPing Rab18 in lipid droplets

• Francesca Zappa ^[1] ; Rossella Venditti ^[1] ; Maria Antonietta De Matteis ^[1]
  1. [1] Telethon Institute Of Genetics And Medicine

     Telethon Institute Of Genetics And Medicine

     Nápoles, Italia

     
• Localización: EMBO journal: European Molecular Biology Organization, ISSN 0261-4189, Vol. 36, Nº. 4, 2017, págs. 394-396
• Idioma: inglés
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• Resumen

  • A number of membrane trafficking components are associated with lipid droplets (LDs) and/or are involved in their biogenesis. In this issue of The EMBO Journal, Li et al (2017) show that the mammalian TRAPPII (TRAnsport Protein Particle) complex acts as an LD‐associated GEF for Rab18, thereby regulating LD homeostasis.