Histiocitosis de células de Langerhans: diferentes manifestaciones de una misma base histopatogénica

J. Martínez Baylach ^[1] ; N. Pardo García ^[1] ; M. Torrent Español ^[1] ; E. Moliner Calderón ^[1] ; I. Anquela Sanz ^[1] ; J. Cubells Rieró ^[1]
1. [1] Hospital de la Santa Creu i Sant Pau
  
  Hospital de la Santa Creu i Sant Pau
  
  Barcelona, España
Localización: Anales españoles de pediatría: Publicación oficial de la Asociación Española de Pediatría ( AEP ), ISSN 0302-4342, Vol. 57, Nº. 5, 2002, págs. 484-487
Idioma: español
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Resumen
- Langerhans' cell histiocytosis (LCH), previously known as histiocytosis X, is a rare disease. It is characterized by the accumulation and proliferation of histiocytes, eosinophils and Langerhans' cells with Birbeck granules detected by electron microscopy. It involves single organs or systems or can present as a multisystem disease. The clinical presentation may vary widely, ranging from benign self-limiting types with spontaneous regression to slowly-progressive malignant disease. We report five cases of LCH with the same histopathologic basis but different outcome.