Resumen de Posterior polymorphous dystrophy and keratoconus: more than a casual association?

Luis F. Mejía, Diego Aristizábal Montes, Juan M. Palacio, Natalia L. Calle

• PURPOSE: To report the simultaneous presentation of Posterior Polymorphous Corneal Dystrophy and Keratoconus in a group of patients from the Cornea and External Diseases Clinic at CES University, between 1995 and 2008 and provide a plausible explanation for it.

  METHODS: This is a retrospective clinical records review of patients with simultaneous presentation of Posterior Polymorphous Corneal Dystrophy and Keratoconus who had undergone a complete ophthalmological examination; the diagnosis of Posterior Polymorphous Corneal Dystrophy was based on clinical findings on slit lamp examination and the diagnosis of Keratoconus was confirmed by corneal topography.

  RESULTS: We identified five patients with a simultaneous clinical presentation of Posterior Polymorphous Corneal Dystrophy and Keratoconus.

  CONCLUSIONS: Weighing the facts, there is a possible association between Posterior Polymorphous Corneal Dystrophy and Keratoconus well beyond simple chance, explained on the basis of a common embryological origin together with simultaneous chromosomal alterations, justifying their simultaneous presentation.