Panoramic and skull imaging may aid in the identification of multiple myeloma lesions

• Karina-Morais Faria ^[6] ; Thais-Bianca Brandão ^[6] ; Wagner-Gomes Silva ^[6] ; Juliana Pereira ^[2] ; Frederico-Sampaio Neves ^[1] ; Marcelo-Corrêa Alves ^[2] ; Werner-Harumiti Shintaku ^[3] ; Marcio-Ajudarte Lopes ^[4] ; Carolina-Prado Ribeiro ^[2] ; Cesar-Augusto Migliorati ^[3] ; Alan-Roger Santos-Silva ^[5]
  1. [1] Universidade Federal da Bahia

     Universidade Federal da Bahia

     Brasil

     
  2. [2] Universidade de São Paulo

     Universidade de São Paulo

     Brasil

     
  3. [3] University of Tennessee Health Science Center

     University of Tennessee Health Science Center

     Estados Unidos

     
  4. [4] Oral Diagnosis Department, Semiology Area, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil. Av. Limeira, 901, Areão, Piracicaba, São Paulo, Brazil, CEP: 13414-903
  5. [5] Oral Diagnosis Department, Semiology Area, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil. Av. Limeira, 901, Areão, Piracicaba, São Paulo, Brazil, CEP: 13414-903; Dental Oncology Service, Instituto do Câncer do Estado de São Paulo [ICESP], Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil. Av. Dr. Arnaldo, 251, Cerqueira César, São Paulo, Brazil, CEP: 01246-000; Shared senior authors
  6. [6] Oral Diagnosis Department, Semiology Area, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil. Av. Limeira, 901, Areão, Piracicaba, São Paulo, Brazil, CEP: 13414-903; Dental Oncology Service, Instituto do Câncer do Estado de São Paulo [ICESP], Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil. Av. Dr. Arnaldo, 251, Cerqueira César, São Paulo, Brazil, CEP: 01246-000

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• Localización: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, ISSN-e 1698-6946, Vol. 23, Nº. 1 (January ), 2018
• Idioma: inglés
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• Resumen

  • The purpose of this study was to investigate the presence of punched-out lesions in craniofacial bones using three different radiographic protocols in a large cohort of patients.

    One hundred fifty-five MM patients were evaluated using panoramic and skull (frontal and lateral) radiographs, which were performed in all patients at the time of MM diagnosis. The diagnostic potential for detecting punched-out lesions was compared among the radiographic techniques.

    MM punched-out lesions were identified in 135 (87%) panoramic radiographs, 141 (91%) frontal and 144 (93%) lateral skull radiographs. Punched out-lesions were synchronously present in skull and jawbones in 129 (83.23 %) cases. The lesions were detected exclusively in skull in 18 (11.61%) cases and exclusively in jawbones in 6 (3.87%) cases. Punched out-lesion mainly affected the skull and the jawbones in a synchronous way (p<0.001) rather than separately.

    All investigated radiographic techniques (panoramic, frontal and lateral skull approaches) demonstrated high detection rates for MM punched-out lesions in craniofacial bones. Panoramic radiography may aid to the radiographic protocols to identify multiple myeloma bone lesions.