Spatial correlations in the melting transition of genomic fiber DNA in solution

• Adrían González ^{[1] [2]} ; Andrew Wildes ^[1] ; Santiago Cuesta-López ^[2] ; Michel Peyrard ^[3]
  1. [1] Institut Laue-Langevin

     Institut Laue-Langevin

     Arrondissement de Grenoble, Francia

     
  2. [2] Universidad de Burgos

     Universidad de Burgos

     Burgos, España

     
  3. [3] École Normale Supérieure de Lyon

     École Normale Supérieure de Lyon

     Arrondissement de Lyon, Francia

     

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• Localización: III Jornadas de Doctorandos de la Universidad de Burgos: Universidad de Burgos, 15 y 16 de diciembre de 2016 / coord. por José Luis Cuesta Gómez; Joaquín A. Pacheco Bonrostro (dir.), 2016, ISBN 978-84-16283-30-9, págs. 285-290
• Idioma: inglés
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• Resumen

  • The melting of DNA is a phase transition which proves interesting due both to theoretical implications and current applications in bio-labs. Moreover it may have something to say in our general view of the statistic mechanic of DNA and s0 in our understanding of some biological processes. ln this work we use neutron scattering on highly oriented DNA fibers submerged in polymer solutions with different osmotic pressures aiming to study the effects of the DNA confinement on this still not totally understood transition. lt has been discovered that samples under higher osmotic pressure, this is more constricted, seems to undergo sharper meltings. Also, the nature of this submerged fibers seem to prevent the macroscopic collapse which hindered previous studies in similar humidified samples.