This paper concerns the comparative historical research of the cultural regimes of knowledge transfer in the early modern period. It compares the cultural regimes in China, India and Japan, which patronised or restrained the diffusion of the western scientific orientation introduced by the Jesuits missionaries in the sixteenth and seventeenth centuries. The periodisation accords with the late Ming (1368-1644) and the early Qing (1644- 1911) dynasties in China, the early Tokugawa period (1603-1868) in Japan, and the Mughal Empire and southern princely states in India.
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