Further research and applications in the field of ozone therapy: Much more than a "Therapeutic Unconventional Hypothesis".

• Autores: Lamberto Re, Giuseppe Malcangi, Cristina Gagliardi, Oriano Mercante
• Localización: Journal of Ozone Therapy (JO3T), ISSN-e 2444-9865, Vol. 1, Nº. 1, 2015, págs. 1-1
• Idioma: inglés
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• Resumen

  • Ozone therapy is widely used in many countries since many years. Recently, the increasing widespread of this complementary therapy has been accomplished by an increased number of basic and clinic papers published on international journals. Many of the basic mechanisms of the ozone action are now well outlined. In addition, the modulation of interleukins and of some biochemical pathways related to inflammation and pain, indicates the rationale for its use in many pathological conditions related to pain, inflammation and age disorders. We will discuss on the mode of action of ozone that, with a hormetic mechanism, appear to be more similar to xenobiotic stress model than a pure pharmacological action. Indeed, our recent work in vivo on patients treated with major autohemo therapy (MAH) demonstrated the increase of Nrf2 level (P