Transplants from animals are a step closer, after the birth of piglets that have had harmful viruses in their DNA inactivated using gene editing. Luhan Yang of Boston biotech firm eGenesis and colleagues previously used the gene-editing technique CRISPR to disable porcine endogenous retroviruses (PERVs) in pig cells grown in a dish. Now they have taken genetic material from such cells and, using a similar technique to the one used to clone Dolly the sheep, put it into pig eggs. They then implanted these into sows, which went on to give birth to clones that are the first PERV-free pigs.
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