There's ample evidence of breeding between Neanderthals and the ancestors of modern humans some 50,000 years ago. Analysis of mitochondrial DNA from a Neanderthal femur found in south-western Germany now adds to evidence that there was earlier interbreeding. Puzzlingly, the mtDNA in Neanderthal bones is more similar to that of modern humans than it is to that of the Denisovans.
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